Chief of Detectives Robert Ironside (Raymond Burr) is shot down by a sniper's bullet while vacationing at a remote cabin. Surviving the assassination attempt, Ironside is left paralyzed from the waist down. Confined to a wheelchair, he becomes the head of his own special police unit, solving crimes with a crack team of investigators on the streets of San Francisco.

Set during the turbulent '60s, Ironside - Season One confronted the hottest issues of its time—civil rights, drugs, hippies, rock 'n' roll—and gave television its first disabled hero. Ironside’s inaugural season attracted many special guest stars—including Jack Lord, Susan Saint James, David Carradine and Gary Collins, among many others—as it began its eight-year run as destination television for millions of Americans.